Of the 2,500 patients in the study, about 70 suffered stroke or heart attack, and 23 died. The trial studied patients in their 70s with no previous history of cardivascular problems. This is the first time such concerns have been raised about naproxen.
The FDA now recommends that Aleve not be taken for more than 10 days. Aleve is an over-the-counter medication, and not a prescription drug. Officials urge users to follow label directions carefully.
Doctors note that these medications were initially conceived for short term pain relief, and were not intended for long-term use with higher doses. The effects of long-term use had not been previously scrutinized. Aleve is manufactured by Bayer.